In this paper, we present a novel and efficient method for brain tumor (and sub regions) segmentation in multimodal MR images based on a fully convolutional network (FCN) that enables end-to-end training and fast inference. Our structure consists of a downsampling path and three upsampling paths, which extract multi-level contextual information by concatenating hierarchical feature representation from each upsampling path. Meanwhile, we introduce a symmetry-driven FCN by the proposal of using symmetry difference images. The model was evaluated on Brain Tumor Image Segmentation Benchmark (BRATS) 2013 challenge dataset and achieved the state-of-the-art results while the computational cost is less than competitors.
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